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A infografia mostra como funciona a vacina AstraZeneca/Oxford.


A vacina AstraZeneca/Oxford pode ser 90% eficaz

By Duncan Mil

November 23, 2020 - A vacina da Universidade de Oxford e da AstraZeneca pode evitar que
até 90% das pessoas contraiam coronavírus quando administrada em
meia dose seguida pela dose completa pelo menos um mês mais tarde.

The vaccine’s effectiveness depends on the dosing regimens -- it fell to just 62% when given as two full doses rather than a half-dose first. But scientists cautioned against seeing this as evidence that it would be less useful than rival vaccines from Pfizer/BioNTech and Moderna. These vaccines each prevented about 95% of cases according to interim data from their late-stage studies.

Oxford and AstraZeneca also said that there were no hospitalized or severe cases of the coronavirus in anyone who received the vaccine. They had also seen a reduction in asymptomatic infections, suggesting that the vaccine could reduce transmission.

The vaccine uses a chimpanzee adenovirus as a vector to carry the gene of the so-called surface spike protein. The coronavirus uses the spike protein to enter human cells to replicate.

After vaccination, the spike protein primes the immune system to attack the coronavirus if it later infects the body.

PUBLISHED: 23/11/2020; STORY: Graphic News